diff --git a/src/amd/vulkan/radv_device.c b/src/amd/vulkan/radv_device.c
index 9c4ce0172d5..6d4b83580eb 100644
--- a/src/amd/vulkan/radv_device.c
+++ b/src/amd/vulkan/radv_device.c
@@ -619,6 +619,14 @@ radv_handle_per_app_options(struct radv_instance *instance,
 			/* Fix various artifacts in Detroit: Become Human */
 			instance->debug_flags |= RADV_DEBUG_ZERO_VRAM |
 			                         RADV_DEBUG_DISCARD_TO_DEMOTE;
+
+			/* Fix rendering issues in Detroit: Become Human
+			 * because the game uses render loops (it
+			 * samples/renders from/to the same depth/stencil
+			 * texture inside the same draw) without input
+			 * attachments and that is invalid Vulkan usage.
+			 */
+			instance->disable_tc_compat_htile_in_general = true;
 		}
 	}
 
diff --git a/src/amd/vulkan/radv_image.c b/src/amd/vulkan/radv_image.c
index 6ecd0ac3d7a..80d1401583f 100644
--- a/src/amd/vulkan/radv_image.c
+++ b/src/amd/vulkan/radv_image.c
@@ -1841,7 +1841,8 @@ bool radv_layout_is_htile_compressed(const struct radv_device *device,
 		 */
 		if (radv_image_is_tc_compat_htile(image) &&
 		    queue_mask & (1u << RADV_QUEUE_GENERAL) &&
-		    !in_render_loop) {
+		    !in_render_loop &&
+		    !device->instance->disable_tc_compat_htile_in_general) {
 			/* GFX10+ supports compressed writes to HTILE. */
 			return device->physical_device->rad_info.chip_class >= GFX10 ||
 			       !(image->usage & VK_IMAGE_USAGE_STORAGE_BIT);
diff --git a/src/amd/vulkan/radv_private.h b/src/amd/vulkan/radv_private.h
index 09dbe148621..c273eae2ba3 100644
--- a/src/amd/vulkan/radv_private.h
+++ b/src/amd/vulkan/radv_private.h
@@ -360,6 +360,7 @@ struct radv_instance {
 	 * Workarounds for game bugs.
 	 */
 	bool enable_mrt_output_nan_fixup;
+	bool disable_tc_compat_htile_in_general;
 };
 
 VkResult radv_init_wsi(struct radv_physical_device *physical_device);